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The Maximus model is the most streamlined of the three and the easiest to start, which is its main draw

these findings are modeldependent and primarily preclinical (see Key references)

FOXO4-DRI is a large peptide (~5382 Da, 48 amino acids) with a critical structural modification: the D-Retro-Inverso (DRI) design uses D-amino acids in reversed sequence to confer protease resistance while maintaining the 3D spatial arrangement needed for target binding

DNA damage response and regulation of cytoskeleton organization were also prominently represented in MitoQ IC50 treatment compared to control (LIMK1, LIMK2, TESK1, CAMK4, CAMK2B, PKACA, ERK1) ( Figure 6B )